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  • Dr. J. James Frost

Cardiac Imaging

Updated: May 10

Cardiac imaging has been a focal point of Dr. Frost and BioMolecular Imaging for decades. This extends from functional heart imaging in the clinic to novel first-in-human molecular imaging. One example is the first human PET imaging of the cardiac muscle membrane potential using a new F-18 triphenylphosphonium cation.

Another example is the first imaging of the mu and delta opiate receptors in the heart, an unexpected and novel finding. As with other organ systems, Dr. Frost and BioMolecular Imaging are able to assist you in developing any complex strategy involving cardiac imaging.

Cardiac mu opiate receptors before and after naloxone antagonist administration.

In the area of commercial development, Dr. Frost has similarly been an active presence for many pharmaceutical industry partners; first-time biotech companies embarking on molecular imaging ventures; bringing new molecular imaging probes to FDA approval; and helping launch new agents by chairing company advisory boards and educating the clinic physicians.

He is also a board-certified radiologist and nuclear medicine physician and has a PhD in nuclear and radiochemistry. Accordingly, he is capable of achieving the first high-level evaluation for any new project and then helping develop the in-depth components that immediately follow. When subdomain expertise is needed, Dr. Frost can draw on a long list of specialists in radiochemistry, physics, imaging CROs, and others and bring them to the table.

About BioMolecular Imaging

BioMolecular Imaging (BMI Consultants) is a molecular imaging and clinical trial consultancy owned and operated by Dr. J. James Frost M.D./Ph.D out of Baltimore Maryland. BMI has been involved with clinical, therapeutic & diagnostic imaging focused on Oncology, Brain, Biomarkers, Cardiology and Central Image Interpretations for over 20 years.

To learn more about BioMolecular Imaging, please visit or connect with:

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BioMolecular Imaging is a registered trademark of BioMolecular Imaging D.B.A. BMI Consultants

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